Executive Functioning and implicated brain recruitment distinctions in youth antisocial phenotypes

Last updated on Nov 1, 2023

Executive functioning is a ubiquitous and transdiagnostic factor across mental health symptoms - and implications in youth antisocial phenotypes are mixed. This project seeks to determine distinctions in executive functions betwen distinct (yet related) antisocial phenotypes as well as their contributions to charactistic impairments vis implicated brain properties.

Theory of Mind Executive Function Cognitive Control Callous-Unemotional Traits Experimental Design fMRI Functional Connectivity
Drew E. Winters, PhD.
Drew E. Winters, PhD.
Assistant Professor of Psychiatry

My research interests include mental and social health, as well as their associated neural processes across the lifespan. In this vein, I am interested in applying quantitative methods to identify replicable neural mechanisms that may improve testing and development of interventions for youth with callous-unemotional traits.

Related

Publications

The dark sides of the brain: A systematic review and meta-analysis of functional neuroimaging studies on trait aggression
This project examined functional brain features of aggression across the literature
Jules Dugre, Christian Hopfer, Drew E. Winters
PDF Project DOI
Affective theory of mind impairments linked with callous-unemotional traits implicate cognitive control: A pre-registered double-blind randomized controlled trial with a dual-task paradigm
Introduction- Youth antisocial behavior strongly associates with conduct problems (CP) and callous-unemotional (CU) traits. While CP …
Drew E. Winters, Juliet Spitz, Kristen Raymond, Crystal Natvig, Rebecca Waller, Susan K. Mikulich-Gilbertson, Joseph T. Sakai
Preprint PDF Code Project DOI
Callous-Unemotional Trait Prosocial Limitations Are Moderated by Cognitive Control Impacting Theory of Mind in Adolescents
Although callous-unemotional (CU) traits are linked with antisocial behavior, affected youth still engage in some prosocial behaviors. …
Drew E. Winters, Joseph T. Sakai
PDF Project DOI
Cognitive Control Difficulties Differentiate Callous-Unemotional Traits from Conduct Problems: A Pre-Registered Double-Blind Randomized Controlled Trial Analysis
Introduction- Youth antisocial behavior strongly associates with conduct problems (CP) and callous-unemotional (CU) traits. While CP …
Drew E. Winters, Juliet Spitz, Kristen Raymond, Crystal Natvig, Rebecca Waller, Susan K. Mikulich-Gilbertson, Joseph P. Schacht, Joseph T. Sakai
PDF Code Project DOI
Effects of COMT Suppression in a Randomized Trial on the Neural Correlates of Inhibitory Processing Among People With Alcohol Use Disorder
Introduction- Youth antisocial behavior strongly associates with conduct problems (CP) and callous-unemotional (CU) traits. While CP …
Drew E. Winters, Joseph P. Schacht
PDF Project DOI
Executive function and underlying brain network distinctions for callous-unemotional traits and conduct problems in adolescents
This project employed advanced statistical approaches to redress issues in the field examining antisocial phenotypes in relation to executive functions. We found some support for existing literature while extending it to demonstrate distinct brain and executive function associations in the presence of Callout-Unemotional traits and Conduct Problems.
Drew E. Winters, Jules Dugre, R. Mckell Carter, Joseph T. Sakai
Preprint PDF Code Project DOI
Executive function and underlying brain network distinctions for callous-unemotional traits and conduct problems in adolescents